HBV Target gene Detail Information

> GTF2H5 Gene Search Result


Gene Information
Gene Name GTF2H5
Gene ID 404672
Gene Full Name general transcription factor IIH subunit 5
Gene Alias TTD; TFB5; TTD3; TTDA; TFIIH; TTD-A; TGF2H5; C6orf175; bA120J8.2
Transcripts ENSG00000272047
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q6ZYL4
HGNC ID HGNC:21157
VEGA ID OTTHUMG00000015906
OMIM ID 608780
String ID 9606.ENSP00000476100
PharmGKB ID PA134962077
Target gene [GTF2H5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008936 chr6 16 2 18 View
1009314 chr6 14 2 16 View
1404798 chr6 10 15 61 86 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GTF2H5 expression and immune infiltrating cell level correlation result in HBV+ samples
GTF2H5 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).