HIV Target gene Detail Information

> GTF2H3 Gene Search Result

Gene Information

Gene Name	GTF2H3
Gene ID	2967
Gene Full Name	general transcription factor IIH subunit 3
Gene Alias	P34; BTF2; TFB4; TFIIH
Transcripts	ENSG00000111358
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q13889
HGNC ID	HGNC:4657
VEGA ID	OTTHUMG00000168697
OMIM ID	601750
String ID	9606.ENSP00000445162
PharmGKB ID	PA29043

Target gene [GTF2H3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009525	chr12	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GTF2H3 expression and immune infiltrating cell level correlation result in HIV+ samples
GTF2H3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GTF2H3 expression and immune infiltrating cell level correlation result in HIV+ samples
GTF2H3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).