HIV Target gene Detail Information

> GTF2A2 Gene Search Result

Gene Information

Gene Name	GTF2A2
Gene ID	2958
Gene Full Name	general transcription factor IIA subunit 2
Gene Alias	TF2A2; TFIIA; T18745; TFIIAS; HsT18745; TFIIA-12; TFIIA-gamma
Transcripts	ENSG00000140307
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P52657
HGNC ID	HGNC:4647
VEGA ID	OTTHUMG00000132725
OMIM ID	600519
String ID	9606.ENSP00000379372
PharmGKB ID	PA29034

Target gene [GTF2A2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003697	chr15	41	15		56	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GTF2A2 expression and immune infiltrating cell level correlation result in HIV+ samples
GTF2A2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GTF2A2 expression and immune infiltrating cell level correlation result in HIV+ samples
GTF2A2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).