HPV Target gene Detail Information

> GSX2 Gene Search Result

Gene Information

Gene Name	GSX2
Gene ID	170825
Gene Full Name	GS homeobox 2
Gene Alias	GSH2
Transcripts	ENSG00000180613
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9BZM3
HGNC ID	HGNC:24959
VEGA ID	OTTHUMG00000128696
OMIM ID	616253
String ID	9606.ENSP00000319118
PharmGKB ID	PA162390374

Target gene [GSX2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402799	chr4	103	18	13	134	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of GSX2 expression and immune infiltrating cell level correlation result in HPV+ samples
GSX2 expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of GSX2 expression and immune infiltrating cell level correlation result in HPV+ samples
GSX2 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of GSX2 expression and immune infiltrating cell level correlation result in HPV+ samples
GSX2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).