HBV Target gene Detail Information

> GSTA1 Gene Search Result


Gene Information
Gene Name GSTA1
Gene ID 2938
Gene Full Name glutathione S-transferase alpha 1
Gene Alias GST2; GTH1; GSTA1-1; GST-epsilon
Transcripts ENSG00000243955
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P08263
HGNC ID HGNC:4626
VEGA ID OTTHUMG00000014861
OMIM ID 138359
String ID 9606.ENSP00000335620
Drugbank ID BE0002281; BE0010006
PharmGKB ID PA29016
Target gene [GSTA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004891 chr6 67 67 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of GSTA1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
GSTA1 expression: Low -> High
Lollipop of GSTA1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of GSTA1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GSTA1 expression and immune infiltrating cell level correlation result in HBV+ samples
GSTA1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).