HTLV1 Target gene Detail Information

> GSDMD Gene Search Result

Gene Information

Gene Name	GSDMD
Gene ID	79792
Gene Full Name	gasdermin D
Gene Alias	DF5L; DFNA5L; FKSG10; GSDMDC1
Transcripts	ENSG00000278718
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transporters
Uniport_ID	P57764
HGNC ID	HGNC:25697
VEGA ID	OTTHUMG00000190667
OMIM ID	617042
String ID	9606.ENSP00000433209
PharmGKB ID	PA162390357

Target gene [GSDMD] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6003884	chr8	51	85	1	137	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of GSDMD expression and immune infiltrating cell level correlation result in HTLV1+ samples
GSDMD expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).