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HPV Target gene Detail Information

> GSDMA Gene Search Result


Gene Information
Gene Name GSDMA
Gene ID 284110
Gene Full Name gasdermin A
Gene Alias GSDM; FKSG9; GSDM1
Transcripts ENSG00000167914
Virus HPV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transporters
Uniport_ID Q96QA5
HGNC ID HGNC:13311
VEGA ID OTTHUMG00000179522
OMIM ID 611218
String ID 9606.ENSP00000301659
PharmGKB ID PA162390274
Target gene [GSDMA] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403535 chr17 182 195 24 401 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of GSDMA expression and immune infiltrating cell level correlation result in HPV+ samples
GSDMA expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of GSDMA expression and immune infiltrating cell level correlation result in HPV+ samples
GSDMA expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of GSDMA expression and immune infiltrating cell level correlation result in HPV+ samples
GSDMA expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of GSDMA expression and immune infiltrating cell level correlation result in HPV+ samples
GSDMA expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of GSDMA expression and immune infiltrating cell level correlation result in HPV+ samples
GSDMA expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of GSDMA expression and immune infiltrating cell level correlation result in HPV+ samples
GSDMA expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of GSDMA expression and immune infiltrating cell level correlation result in HPV+ samples
GSDMA expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).