HBV Target gene Detail Information

> GRM8 Gene Search Result

Gene Information

Gene Name	GRM8
Gene ID	2918
Gene Full Name	glutamate metabotropic receptor 8
Gene Alias	GLUR8; mGlu8; GPRC1H; MGLUR8
Transcripts	ENSG00000179603
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O00222
HGNC ID	HGNC:4600
VEGA ID	OTTHUMG00000022888
OMIM ID	601116
String ID	9606.ENSP00000344173
Drugbank ID	BE0000835
PharmGKB ID	PA28997

Target gene [GRM8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013849	chr7	2	2		4	View
1014837	chr7		3		3	View
1015603	chr7	2			2	View
1015735	chr7	2			2	View
1016594	chr7	1			1	View
1016595	chr7			1	1	View
1017249	chr7	1			1	View
1019812	chr7				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GRM8 expression and immune infiltrating cell level correlation result in HBV+ samples
GRM8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).