HBV Target gene Detail Information

> GRM7 Gene Search Result

Gene Information

Gene Name	GRM7
Gene ID	2917
Gene Full Name	glutamate metabotropic receptor 7
Gene Alias	GLUR7; MGLU7; GPRC1G; MGLUR7; PPP1R87
Transcripts	ENSG00000196277
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q14831
HGNC ID	HGNC:4599
VEGA ID	OTTHUMG00000125549
OMIM ID	604101
String ID	9606.ENSP00000350348
Drugbank ID	BE0000834
PharmGKB ID	PA28996

Target gene [GRM7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009293	chr3	15	1		16	View
1010297	chr3	1	1	10	12	View
1015925	chr3	1	1		2	View
1017516	chr3				0	View
1017551	chr3				0	View
1402529	chr3	15	1		16	View
1404316	chr3				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GRM7 expression and immune infiltrating cell level correlation result in HBV+ samples
GRM7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).