HBV Target gene Detail Information

> GRM1 Gene Search Result


Gene Information
Gene Name GRM1
Gene ID 2911
Gene Full Name glutamate metabotropic receptor 1
Gene Alias MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85
Transcripts ENSG00000152822
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters
Gene Function Oncogene
Uniport_ID Q13255
HGNC ID HGNC:4593
VEGA ID OTTHUMG00000015752
OMIM ID 604473
String ID 9606.ENSP00000354896
Drugbank ID BE0000824
PharmGKB ID PA28990
Target gene [GRM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005048 chr6 6 22 35 63 View
1012476 chr6 3 4 7 View
1018619 chr6 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GRM1 expression and immune infiltrating cell level correlation result in HBV+ samples
GRM1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).