HIV Target gene Detail Information

> GRK7 Gene Search Result

Gene Information

Gene Name	GRK7
Gene ID	131890
Gene Full Name	G protein-coupled receptor kinase 7
Gene Alias	GPRK7
Transcripts	ENSG00000114124
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8WTQ7
HGNC ID	HGNC:17031
VEGA ID	OTTHUMG00000159068
OMIM ID	606987
String ID	9606.ENSP00000264952
PharmGKB ID	PA38433

Target gene [GRK7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011760	chr3	4	2		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GRK7 expression and immune infiltrating cell level correlation result in HIV+ samples
GRK7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).