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HBV Target gene Detail Information

> GRIN2B Gene Search Result


Gene Information
Gene Name GRIN2B
Gene ID 2904
Gene Full Name glutamate ionotropic receptor NMDA type subunit 2B
Gene Alias NR3; MRD6; NR2B; hNR3; EIEE27; GluN2B; NMDAR2B
Transcripts ENSG00000273079
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins
Uniport_ID Q13224
HGNC ID HGNC:4586
VEGA ID OTTHUMG00000137373
OMIM ID 138252
String ID 9606.ENSP00000477455
Drugbank ID BE0000417
PharmGKB ID PA28980
Target gene [GRIN2B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011676 chr12 8 8 View
1404496 chr12 4 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GRIN2B expression and immune infiltrating cell level correlation result in HBV+ samples
GRIN2B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).