HBV Target gene Detail Information

> GRIN2A Gene Search Result


Gene Information
Gene Name GRIN2A
Gene ID 2903
Gene Full Name glutamate ionotropic receptor NMDA type subunit 2A
Gene Alias LKS; EPND; FESD; NR2A; GluN2A; NMDAR2A
Transcripts ENSG00000183454
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters
Gene Function Suppressor gene
Uniport_ID Q12879
HGNC ID HGNC:4585
VEGA ID OTTHUMG00000129721
OMIM ID 138253
String ID 9606.ENSP00000379818
Drugbank ID BE0000760
PharmGKB ID PA28979
Target gene [GRIN2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004172 chr16 23 14 53 90 View
1011610 chr16 5 2 1 8 View
1400471 chr16 12 39 56 107 View
1403316 chr16 5 2 1 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GRIN2A expression and immune infiltrating cell level correlation result in HBV+ samples
GRIN2A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).