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HBV Target gene Detail Information

> GRIN1 Gene Search Result


Gene Information
Gene Name GRIN1
Gene ID 2902
Gene Full Name glutamate ionotropic receptor NMDA type subunit 1
Gene Alias NR1; MRD8; GluN1; NMDA1; NDHMSD; NDHMSR; NMD-R1; NMDAR1
Transcripts ENSG00000176884
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters
Uniport_ID Q05586
HGNC ID HGNC:4584
VEGA ID OTTHUMG00000020976
OMIM ID 138249
String ID 9606.ENSP00000360608
Drugbank ID BE0000365
PharmGKB ID PA28978
Target gene [GRIN1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1404529 chr9 26 58 50 134 View
1404533 chr9 26 58 50 134 View
1404538 chr9 26 58 50 134 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GRIN1 expression and immune infiltrating cell level correlation result in HBV+ samples
GRIN1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).