HBV Target gene Detail Information

> GRIK3 Gene Search Result

Gene Information

Gene Name	GRIK3
Gene ID	2899
Gene Full Name	glutamate ionotropic receptor kainate type subunit 3
Gene Alias	EAA5; GLR7; GLUR7; GluK3; GluR7a
Transcripts	ENSG00000163873
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins
Uniport_ID	Q13003
HGNC ID	HGNC:4581
VEGA ID	OTTHUMG00000004189
OMIM ID	138243
String ID	9606.ENSP00000362183
Drugbank ID	BE0000832; BE0009793
PharmGKB ID	PA28975

Target gene [GRIK3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010097	chr1	9	4		13	View
1014631	chr1	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GRIK3 expression and immune infiltrating cell level correlation result in HBV+ samples
GRIK3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).