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HBV Target gene Detail Information

> GRIK2 Gene Search Result


Gene Information
Gene Name GRIK2
Gene ID 2898
Gene Full Name glutamate ionotropic receptor kainate type subunit 2
Gene Alias EAA4; GLR6; MRT6; GLUK6; GLUR6; GluK2
Transcripts ENSG00000164418
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q13002
HGNC ID HGNC:4580
VEGA ID OTTHUMG00000016328
OMIM ID 138244
String ID 9606.ENSP00000397026
Drugbank ID BE0000826; BE0009793
PharmGKB ID PA164741600
Target gene [GRIK2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006088 chr6 1 10 32 43 View
1013090 chr6 5 5 View
1015435 chr6 2 2 View
1019753 chr6 0 View
1403266 chr6 5 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GRIK2 expression and immune infiltrating cell level correlation result in HBV+ samples
GRIK2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).