HBV Target gene Detail Information

> GRIK1 Gene Search Result

Gene Information

Gene Name	GRIK1
Gene ID	2897
Gene Full Name	glutamate ionotropic receptor kainate type subunit 1
Gene Alias	EAA3; EEA3; GLR5; GLUR5; GluK1; gluR-5
Transcripts	ENSG00000171189
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted membrane proteins
Uniport_ID	P39086
HGNC ID	HGNC:4579
VEGA ID	OTTHUMG00000078879
OMIM ID	138245
String ID	9606.ENSP00000382791
Drugbank ID	BE0000346; BE0009793
PharmGKB ID	PA28973

Target gene [GRIK1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006698	chr21	32	3		35	View
1007141	chr21	28	2		30	View
1008954	chr21		15	3	18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GRIK1 expression and immune infiltrating cell level correlation result in HBV+ samples
GRIK1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).