HBV Target gene Detail Information

> GRID2 Gene Search Result

Gene Information

Gene Name	GRID2
Gene ID	2895
Gene Full Name	glutamate ionotropic receptor delta type subunit 2
Gene Alias	GluD2; SCAR18
Transcripts	ENSG00000152208
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O43424
HGNC ID	HGNC:4576
VEGA ID	OTTHUMG00000130975
OMIM ID	602368
String ID	9606.ENSP00000282020
PharmGKB ID	PA28971

Target gene [GRID2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011456	chr4	1	8		9	View
1012418	chr4		1	6	7	View
1013222	chr4		5		5	View
1013223	chr4		5		5	View
1014210	chr4	4			4	View
1017977	chr4				0	View
1018073	chr4				0	View
1018413	chr4				0	View
1019643	chr4				0	View
1400930	chr4				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GRID2 expression and immune infiltrating cell level correlation result in HBV+ samples
GRID2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).