HBV Target gene Detail Information

> GRIA1 Gene Search Result

Gene Information

Gene Name	GRIA1
Gene ID	2890
Gene Full Name	glutamate ionotropic receptor AMPA type subunit 1
Gene Alias	GLUH1; GLUR1; GLURA; GluA1; HBGR1
Transcripts	ENSG00000155511
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Plasma proteins, Predicted membrane proteins
Uniport_ID	P42261
HGNC ID	HGNC:4571
VEGA ID	OTTHUMG00000130148
OMIM ID	138248
String ID	9606.ENSP00000428994
Drugbank ID	BE0000640
PharmGKB ID	PA28966

Target gene [GRIA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009786	chr5	14			14	View
1009787	chr5	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GRIA1 expression and immune infiltrating cell level correlation result in HBV+ samples
GRIA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).