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HBV Target gene Detail Information

> GRHPR Gene Search Result


Gene Information
Gene Name GRHPR
Gene ID 9380
Gene Full Name glyoxylate and hydroxypyruvate reductase
Gene Alias PH2; GLXR; GLYD
Transcripts ENSG00000137106
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q9UBQ7
HGNC ID HGNC:4570
VEGA ID OTTHUMG00000019914
OMIM ID 604296
String ID 9606.ENSP00000313432
PharmGKB ID PA28965
Target gene [GRHPR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005418 chr9 20 35 55 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of GRHPR expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
GRHPR expression: Low -> High
Lollipop of GRHPR expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of GRHPR expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GRHPR expression and immune infiltrating cell level correlation result in HBV+ samples
GRHPR expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).