HBV Target gene Detail Information

> GREM2 Gene Search Result

Gene Information

Gene Name	GREM2
Gene ID	64388
Gene Full Name	gremlin 2, DAN family BMP antagonist
Gene Alias	PRDC; DAND3; STHAG9; CKTSF1B2
Transcripts	ENSG00000180875
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted secreted proteins
Uniport_ID	Q9H772
HGNC ID	HGNC:17655
VEGA ID	OTTHUMG00000039909
OMIM ID	608832
String ID	9606.ENSP00000318650
PharmGKB ID	PA134968998

Target gene [GREM2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004878	chr1	20	18	29	67	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GREM2 expression and immune infiltrating cell level correlation result in HBV+ samples
GREM2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).