HBV Target gene Detail Information

> GRAMD1C Gene Search Result


Gene Information
Gene Name GRAMD1C
Gene ID 54762
Gene Full Name GRAM domain containing 1C
Transcripts ENSG00000178075
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8IYS0
HGNC ID HGNC:25252
VEGA ID OTTHUMG00000159340
String ID 9606.ENSP00000350881
PharmGKB ID PA142671709
Target gene [GRAMD1C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000836 chr3 203 870 298 1371 View
1003526 chr3 105 10 13 128 View
1006953 chr3 31 1 32 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GRAMD1C expression and immune infiltrating cell level correlation result in HBV+ samples
GRAMD1C expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).