HBV Target gene Detail Information

> GPX5 Gene Search Result

Gene Information

Gene Name	GPX5
Gene ID	2880
Gene Full Name	glutathione peroxidase 5
Gene Alias	EGLP; GPx-5; GSHPx-5; HEL-S-75p
Transcripts	ENSG00000257770
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted secreted proteins
Uniport_ID	O75715
HGNC ID	HGNC:4557
VEGA ID	OTTHUMG00000016307
OMIM ID	603435
String ID	9606.ENSP00000392398
Drugbank ID	BE0000820; BE0009997
PharmGKB ID	PA28953

Target gene [GPX5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013099	chr6	2	2	1	5	View
1402975	chr6	2	2	1	5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GPX5 expression and immune infiltrating cell level correlation result in HBV+ samples
GPX5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).