HBV Target gene Detail Information

> GPRC5A Gene Search Result

Gene Information

Gene Name	GPRC5A
Gene ID	9052
Gene Full Name	G protein-coupled receptor class C group 5 member A
Gene Alias	RAI3; TIG1; RAIG1; GPCR5A; PEIG-1
Transcripts	ENSG00000013588
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	Q8NFJ5
HGNC ID	HGNC:9836
VEGA ID	OTTHUMG00000168710
OMIM ID	604138
String ID	9606.ENSP00000014914
Drugbank ID	BE0000697
PharmGKB ID	PA34194

Target gene [GPRC5A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002995	chr12	23	86	69	178	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GPRC5A expression and immune infiltrating cell level correlation result in HBV+ samples
GPRC5A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).