HPV Target gene Detail Information

> GPR89A Gene Search Result

Gene Information

Gene Name	GPR89A
Gene ID	653519
Gene Full Name	G protein-coupled receptor 89A
Gene Alias	GPHR; GPR89; SH120; GPR89B; UNQ192
Transcripts	ENSG00000117262
Virus	HPV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	B7ZAQ6
HGNC ID	HGNC:31984
VEGA ID	OTTHUMG00000013738
OMIM ID	612821
String ID	9606.ENSP00000319673
PharmGKB ID	PA134986137

Target gene [GPR89A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5404359	chr1	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of GPR89A expression and immune infiltrating cell level correlation result in HPV+ samples
GPR89A expression: Low -> High

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of GPR89A expression and immune infiltrating cell level correlation result in HPV+ samples
GPR89A expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of GPR89A expression and immune infiltrating cell level correlation result in HPV+ samples
GPR89A expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of GPR89A expression and immune infiltrating cell level correlation result in HPV+ samples
GPR89A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).