HTLV1 Target gene Detail Information

> GPR173 Gene Search Result

Gene Information

Gene Name	GPR173
Gene ID	54328
Gene Full Name	G protein-coupled receptor 173
Gene Alias	SREB3
Transcripts	ENSG00000184194
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted membrane proteins
Uniport_ID	Q9NS66
HGNC ID	HGNC:18186
VEGA ID	OTTHUMG00000021596
OMIM ID	300253
String ID	9606.ENSP00000331600
PharmGKB ID	PA134896710

Target gene [GPR173] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002454	chrX	162	37	42	241	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of GPR173 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GPR173 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of GPR173 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GPR173 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of GPR173 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GPR173 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).