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HTLV1 Target gene Detail Information

> GPR141 Gene Search Result


Gene Information
Gene Name GPR141
Gene ID 353345
Gene Full Name G protein-coupled receptor 141
Gene Alias PGR13
Transcripts ENSG00000187037
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info G-protein coupled receptors, Predicted membrane proteins
Uniport_ID Q7Z602
HGNC ID HGNC:19997
VEGA ID OTTHUMG00000102105
OMIM ID 609045
String ID 9606.ENSP00000390410
PharmGKB ID PA134923895
Target gene [GPR141] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6010074 chr7 33 33 View
6010095 chr7 33 33 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of GPR141 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GPR141 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of GPR141 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GPR141 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of GPR141 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GPR141 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).