HIV Target gene Detail Information

> GPR137B Gene Search Result

Gene Information

Gene Name	GPR137B
Gene ID	7107
Gene Full Name	G protein-coupled receptor 137B
Gene Alias	TM7SF1
Transcripts	ENSG00000077585
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins, Transporters
Uniport_ID	O60478
HGNC ID	HGNC:11862
VEGA ID	OTTHUMG00000037994
OMIM ID	604658
String ID	9606.ENSP00000355551
PharmGKB ID	PA36563

Target gene [GPR137B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008654	chr1	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GPR137B expression and immune infiltrating cell level correlation result in HIV+ samples
GPR137B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GPR137B expression and immune infiltrating cell level correlation result in HIV+ samples
GPR137B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).