HBV Target gene Detail Information

> GPHN Gene Search Result


Gene Information
Gene Name GPHN
Gene ID 10243
Gene Full Name gephyrin
Gene Alias GPH; GEPH; HKPX1; GPHRYN; MOCODC
Transcripts ENSG00000171723
Virus HBV
Gene Type protein coding
HPA Location Info Cytoplasmic bodies;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q9NQX3
HGNC ID HGNC:15465
VEGA ID OTTHUMG00000029785
OMIM ID 603930
String ID 9606.ENSP00000417901
Drugbank ID BE0002652
PharmGKB ID PA28840
Target gene [GPHN] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004064 chr14 7 50 38 95 View
1010248 chr14 12 1 13 View
1011173 chr14 9 1 10 View
1012309 chr14 1 3 3 7 View
1015227 chr14 2 2 View
1015666 chr14 1 1 2 View
1016864 chr14 1 1 View
1403682 chr14 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GPHN expression and immune infiltrating cell level correlation result in HBV+ samples
GPHN expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).