HIV Target gene Detail Information

> GPD2 Gene Search Result


Gene Information
Gene Name GPD2
Gene ID 2820
Gene Full Name glycerol-3-phosphate dehydrogenase 2
Gene Alias GDH2; GPDM; mGPDH
Transcripts ENSG00000115159
Virus HIV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P43304
HGNC ID HGNC:4456
VEGA ID OTTHUMG00000131951
OMIM ID 138430
String ID 9606.ENSP00000308610
PharmGKB ID PA28837
Target gene [GPD2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006307 chr2 1 19 5 25 View
4010241 chr2 9 9 View
4012812 chr2 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of GPD2 expression and immune infiltrating cell level correlation result in HIV+ samples
GPD2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of GPD2 expression and immune infiltrating cell level correlation result in HIV+ samples
GPD2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).