HBV Target gene Detail Information

> GPC5 Gene Search Result

Gene Information

Gene Name	GPC5
Gene ID	2262
Gene Full Name	glypican 5
Transcripts	ENSG00000179399
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P78333
HGNC ID	HGNC:4453
VEGA ID	OTTHUMG00000017200
OMIM ID	602446
String ID	9606.ENSP00000366267
PharmGKB ID	PA28834

Target gene [GPC5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011596	chr13	4	4		8	View
1013005	chr13		1	5	6	View
1014408	chr13		3		3	View
1017425	chr13		1		1	View
1400547	chr13				0	View
1400717	chr13	4	4		8	View
1403403	chr13		3		3	View
1404358	chr13	2	11	1	14	View
1404839	chr13		3		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GPC5 expression and immune infiltrating cell level correlation result in HBV+ samples
GPC5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).