HIV Target gene Detail Information

> GPC3 Gene Search Result

Gene Information

Gene Name	GPC3
Gene ID	2719
Gene Full Name	glypican 3
Gene Alias	SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2
Transcripts	ENSG00000147257
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	P51654
HGNC ID	HGNC:4451
VEGA ID	OTTHUMG00000022448
OMIM ID	300037
String ID	9606.ENSP00000377836
PharmGKB ID	PA28832

Target gene [GPC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010165	chrX	2	4	3	9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GPC3 expression and immune infiltrating cell level correlation result in HIV+ samples
GPC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).