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HIV Target gene Detail Information

> GON4L Gene Search Result


Gene Information
Gene Name GON4L
Gene ID 54856
Gene Full Name gon-4 like
Gene Alias GON4; YARP; GON-4
Transcripts ENSG00000116580
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q3T8J9
HGNC ID HGNC:25973
VEGA ID OTTHUMG00000014106
OMIM ID 610393
String ID 9606.ENSP00000357315
PharmGKB ID PA142671723
Target gene [GON4L] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001373 chr1 77 72 23 172 View
4001411 chr1 89 26 53 168 View
4002978 chr1 60 13 73 View
4003056 chr1 10 59 2 71 View
4006215 chr1 25 1 26 View
4006563 chr1 22 2 24 View
4006663 chr1 13 8 2 23 View
4010023 chr1 10 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of GON4L expression and immune infiltrating cell level correlation result in HIV+ samples
GON4L expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of GON4L expression and immune infiltrating cell level correlation result in HIV+ samples
GON4L expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).