HTLV1 Target gene Detail Information

> GNRHR2 Gene Search Result

Gene Information

Gene Name	GNRHR2
Gene ID	114814
Gene Alias	GnRH-II-R
Transcripts	ENSG00000211451
Virus	HTLV1
Gene Type	pseudo
HPA Location Info
HGNC ID	HGNC:16341
VEGA ID	OTTHUMG00000013742
OMIM ID	612875
Drugbank ID	BE0000472
PharmGKB ID	PA28801

Target gene [GNRHR2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006340	chr1	70			70	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of GNRHR2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GNRHR2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of GNRHR2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GNRHR2 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of GNRHR2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GNRHR2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).