HIV Target gene Detail Information

> GNPTAB Gene Search Result

Gene Information

Gene Name	GNPTAB
Gene ID	79158
Gene Full Name	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
Gene Alias	ICD; GNPTA
Transcripts	ENSG00000111670
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q3T906
HGNC ID	HGNC:29670
VEGA ID	OTTHUMG00000170444
OMIM ID	607840
String ID	9606.ENSP00000299314
PharmGKB ID	PA128394710

Target gene [GNPTAB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007021	chr12	3	7	11	21	View
4012648	chr12	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GNPTAB expression and immune infiltrating cell level correlation result in HIV+ samples
GNPTAB expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GNPTAB expression and immune infiltrating cell level correlation result in HIV+ samples
GNPTAB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).