HBV Target gene Detail Information

> GNG2 Gene Search Result

Gene Information

Gene Name	GNG2
Gene ID	54331
Gene Full Name	G protein subunit gamma 2
Transcripts	ENSG00000186469
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID	P59768
HGNC ID	HGNC:4404
VEGA ID	OTTHUMG00000171083
OMIM ID	606981
String ID	9606.ENSP00000334448
Drugbank ID	BE0001080
PharmGKB ID	PA28784

Target gene [GNG2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010748	chr14	5	6		11	View
1012137	chr14	3	4		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GNG2 expression and immune infiltrating cell level correlation result in HBV+ samples
GNG2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).