HBV Target gene Detail Information

> GNG12 Gene Search Result


Gene Information
Gene Name GNG12
Gene ID 55970
Gene Full Name G protein subunit gamma 12
Transcripts ENSG00000172380
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Predicted intracellular proteins, RAS pathway related proteins
Uniport_ID Q9UBI6
HGNC ID HGNC:19663
VEGA ID OTTHUMG00000009545
OMIM ID 615405
String ID 9606.ENSP00000360021
PharmGKB ID PA134956700
Target gene [GNG12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003849 chr1 50 55 105 View
1004790 chr1 11 58 69 View
1011328 chr1 6 3 9 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GNG12 expression and immune infiltrating cell level correlation result in HBV+ samples
GNG12 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).