HIV Target gene Detail Information

> GNAQ Gene Search Result

Gene Information

Gene Name	GNAQ
Gene ID	2776
Gene Full Name	G protein subunit alpha q
Gene Alias	GAQ; SWS; CMC1; G-ALPHA-q
Transcripts	ENSG00000156052
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytosol;Plasma membrane;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	P50148
HGNC ID	HGNC:4390
VEGA ID	OTTHUMG00000020059
OMIM ID	600998
String ID	9606.ENSP00000286548
PharmGKB ID	PA174

Target gene [GNAQ] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000564	chr9	71	161	136	368	View
4001318	chr9	145	15	17	177	View
4001405	chr9	70	36	63	169	View
4007125	chr9	16	5		21	View
4008189	chr9	3	1	12	16	View
4011935	chr9	5	1		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GNAQ expression and immune infiltrating cell level correlation result in HIV+ samples
GNAQ expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GNAQ expression and immune infiltrating cell level correlation result in HIV+ samples
GNAQ expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).