HBV Target gene Detail Information

> GNAO1 Gene Search Result

Gene Information

Gene Name	GNAO1
Gene ID	2775
Gene Full Name	G protein subunit alpha o1
Gene Alias	GNAO; NEDIM; EIEE17; HLA-DQB1; G-ALPHA-o
Transcripts	ENSG00000087258
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	P09471
HGNC ID	HGNC:4389
VEGA ID	OTTHUMG00000133241
OMIM ID	139311
String ID	9606.ENSP00000262494
PharmGKB ID	PA28771

Target gene [GNAO1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002622	chr16	71	31	134	236	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GNAO1 expression and immune infiltrating cell level correlation result in HBV+ samples
GNAO1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).