HBV Target gene Detail Information

> GNAI2 Gene Search Result


Gene Information
Gene Name GNAI2
Gene ID 2771
Gene Full Name G protein subunit alpha i2
Gene Alias GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1
Transcripts ENSG00000114353
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;Plasma membrane;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID P04899
HGNC ID HGNC:4385
VEGA ID OTTHUMG00000156940
OMIM ID 139360
String ID 9606.ENSP00000312999
PharmGKB ID PA24347
Target gene [GNAI2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005065 chr3 47 15 62 View
1009274 chr3 10 6 16 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GNAI2 expression and immune infiltrating cell level correlation result in HBV+ samples
GNAI2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).