HIV Target gene Detail Information

> GNA13 Gene Search Result


Gene Information
Gene Name GNA13
Gene ID 10672
Gene Full Name G protein subunit alpha 13
Gene Alias G13
Transcripts ENSG00000120063
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID Q14344
HGNC ID HGNC:4381
VEGA ID OTTHUMG00000179316
OMIM ID 604406
String ID 9606.ENSP00000400717
PharmGKB ID PA28766
Target gene [GNA13] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001963 chr17 107 12 1 120 View
4002071 chr17 92 11 11 114 View
4002417 chr17 54 23 18 95 View
4005644 chr17 17 13 30 View
4006235 chr17 26 26 View
4008154 chr17 9 3 4 16 View
4009144 chr17 12 12 View
4013357 chr17 2 1 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of GNA13 expression and immune infiltrating cell level correlation result in HIV+ samples
GNA13 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of GNA13 expression and immune infiltrating cell level correlation result in HIV+ samples
GNA13 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).