HIV Target gene Detail Information

> GNA13 Gene Search Result

Gene Information

Gene Name	GNA13
Gene ID	10672
Gene Full Name	G protein subunit alpha 13
Gene Alias	G13
Transcripts	ENSG00000120063
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Gene Function	Oncogene
Uniport_ID	Q14344
HGNC ID	HGNC:4381
VEGA ID	OTTHUMG00000179316
OMIM ID	604406
String ID	9606.ENSP00000400717
PharmGKB ID	PA28766

Target gene [GNA13] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001963	chr17	107	12	1	120	View
4002071	chr17	92	11	11	114	View
4002417	chr17	54	23	18	95	View
4005644	chr17	17	13		30	View
4006235	chr17	26			26	View
4008154	chr17	9	3	4	16	View
4009144	chr17	12			12	View
4013357	chr17	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GNA13 expression and immune infiltrating cell level correlation result in HIV+ samples
GNA13 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GNA13 expression and immune infiltrating cell level correlation result in HIV+ samples
GNA13 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).