HIV Target gene Detail Information

> GMPS Gene Search Result

Gene Information

Gene Name	GMPS
Gene ID	8833
Gene Full Name	guanine monophosphate synthase
Gene Alias	GATD7
Transcripts	ENSG00000163655
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P49915
HGNC ID	HGNC:4378
VEGA ID	OTTHUMG00000158551
OMIM ID	600358
String ID	9606.ENSP00000419851
Drugbank ID	BE0000321
PharmGKB ID	PA28763

Target gene [GMPS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006890	chr3	10	12		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GMPS expression and immune infiltrating cell level correlation result in HIV+ samples
GMPS expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GMPS expression and immune infiltrating cell level correlation result in HIV+ samples
GMPS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).