HPV Target gene Detail Information

> GMNC Gene Search Result

Gene Information

Gene Name	GMNC
Gene ID	647309
Gene Full Name	geminin coiled-coil domain containing
Gene Alias	GEMC1
Transcripts	ENSG00000205835
Virus	HPV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	A6NCL1
HGNC ID	HGNC:40049
VEGA ID	OTTHUMG00000156195
OMIM ID	614448
String ID	9606.ENSP00000406164
PharmGKB ID	PA166049067

Target gene [GMNC] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5404329	chr3	24	3		27	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE55546 (GEO)	Oropharyngeal squamous cell carcinoma	16	Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO)	Oropharyngeal squamous cell carcinoma	23	Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of GMNC expression and immune infiltrating cell level correlation result in HPV+ samples
GMNC expression: Low -> High

> Dataset: GSE55546
HeatMap of cell type fractions in all samples	Lollipop of GMNC expression and immune infiltrating cell level correlation result in HPV+ samples
GMNC expression: Low -> High

> Dataset: GSE55544
HeatMap of cell type fractions in all samples	Lollipop of GMNC expression and immune infiltrating cell level correlation result in HPV+ samples
GMNC expression: Low -> High

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of GMNC expression and immune infiltrating cell level correlation result in HPV+ samples
GMNC expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).