HIV Target gene Detail Information

> GMEB2 Gene Search Result

Gene Information

Gene Name	GMEB2
Gene ID	26205
Gene Full Name	glucocorticoid modulatory element binding protein 2
Gene Alias	PIF79; GMEB-2; P79PIF
Transcripts	ENSG00000101216
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9UKD1
HGNC ID	HGNC:4371
VEGA ID	OTTHUMG00000032988
OMIM ID	607451
String ID	9606.ENSP00000266068
PharmGKB ID	PA28756

Target gene [GMEB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003823	chr20	50	2	2	54	View
4005741	chr20	9	20	1	30	View
4009469	chr20	9	2		11	View
4010738	chr20	8			8	View
4010868	chr20	3	5		8	View
4012481	chr20	3	2		5	View
4013475	chr20	1	2		3	View
4013673	chr20	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GMEB2 expression and immune infiltrating cell level correlation result in HIV+ samples
GMEB2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GMEB2 expression and immune infiltrating cell level correlation result in HIV+ samples
GMEB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).