HBV Target gene Detail Information

> GMDS Gene Search Result


Gene Information
Gene Name GMDS
Gene ID 2762
Gene Full Name GDP-mannose 4,6-dehydratase
Gene Alias GMD; SDR3E1
Transcripts ENSG00000112699
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID O60547
HGNC ID HGNC:4369
VEGA ID OTTHUMG00000016143
OMIM ID 602884
String ID 9606.ENSP00000370194
Drugbank ID BE0003278
PharmGKB ID PA28754
Target gene [GMDS] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009509 chr6 12 3 15 View
1014267 chr6 3 1 4 View
1401602 chr6 12 3 15 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GMDS expression and immune infiltrating cell level correlation result in HBV+ samples
GMDS expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).