HBV Target gene Detail Information

> GMDS Gene Search Result

Gene Information

Gene Name	GMDS
Gene ID	2762
Gene Full Name	GDP-mannose 4,6-dehydratase
Gene Alias	GMD; SDR3E1
Transcripts	ENSG00000112699
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	O60547
HGNC ID	HGNC:4369
VEGA ID	OTTHUMG00000016143
OMIM ID	602884
String ID	9606.ENSP00000370194
Drugbank ID	BE0003278
PharmGKB ID	PA28754

Target gene [GMDS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009509	chr6	12	3		15	View
1014267	chr6	3	1		4	View
1401602	chr6	12	3		15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GMDS expression and immune infiltrating cell level correlation result in HBV+ samples
GMDS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).