HIV Target gene Detail Information

> GMCL1 Gene Search Result

Gene Information

Gene Name	GMCL1
Gene ID	64395
Gene Full Name	germ cell-less, spermatogenesis associated 1
Gene Alias	GCL; GCL1; BTBD13; SPATA29
Transcripts	ENSG00000087338
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q96IK5
HGNC ID	HGNC:23843
VEGA ID	OTTHUMG00000129643
OMIM ID	618627
String ID	9606.ENSP00000282570
PharmGKB ID	PA143485477

Target gene [GMCL1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009554	chr2	5	5	1	11	View
4010311	chr2	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GMCL1 expression and immune infiltrating cell level correlation result in HIV+ samples
GMCL1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GMCL1 expression and immune infiltrating cell level correlation result in HIV+ samples
GMCL1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).