HIV Target gene Detail Information

> GM2A Gene Search Result

Gene Information

Gene Name	GM2A
Gene ID	2760
Gene Full Name	GM2 ganglioside activator
Gene Alias	SAP-3; GM2-AP
Transcripts	ENSG00000196743
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P17900
HGNC ID	HGNC:4367
VEGA ID	OTTHUMG00000130124
OMIM ID	613109
String ID	9606.ENSP00000349687
Drugbank ID	BE0001432
PharmGKB ID	PA28752

Target gene [GM2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009700	chr5	2	9		11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GM2A expression and immune infiltrating cell level correlation result in HIV+ samples
GM2A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GM2A expression and immune infiltrating cell level correlation result in HIV+ samples
GM2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).