HTLV1 Target gene Detail Information

> GLRX3 Gene Search Result

Gene Information

Gene Name	GLRX3
Gene ID	10539
Gene Full Name	glutaredoxin 3
Gene Alias	GRX3; GRX4; GLRX4; PICOT; TXNL2; TXNL3
Transcripts	ENSG00000108010
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O76003
HGNC ID	HGNC:15987
VEGA ID	OTTHUMG00000019267
OMIM ID	612754
String ID	9606.ENSP00000357633
PharmGKB ID	PA162389829

Target gene [GLRX3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005458	chr10	60	15	12	87	View
6023549	chr10	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of GLRX3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GLRX3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).