HBV Target gene Detail Information

> GLRA1 Gene Search Result

Gene Information

Gene Name	GLRA1
Gene ID	2741
Gene Full Name	glycine receptor alpha 1
Gene Alias	STHE; HKPX1
Transcripts	ENSG00000145888
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	P23415
HGNC ID	HGNC:4326
VEGA ID	OTTHUMG00000130121
OMIM ID	138491
String ID	9606.ENSP00000411593
Drugbank ID	BE0000433; BE0009666
PharmGKB ID	PA28727

Target gene [GLRA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015198	chr5	1	1		2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GLRA1 expression and immune infiltrating cell level correlation result in HBV+ samples
GLRA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).