HBV Target gene Detail Information

> GLIS3 Gene Search Result

Gene Information

Gene Name	GLIS3
Gene ID	169792
Gene Full Name	GLIS family zinc finger 3
Gene Alias	NDH; ZNF515
Transcripts	ENSG00000107249
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q8NEA6
HGNC ID	HGNC:28510
VEGA ID	OTTHUMG00000019463
OMIM ID	610192
String ID	9606.ENSP00000371398
PharmGKB ID	PA134878768

Target gene [GLIS3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003096	chr9	146	16	5	167	View
1012140	chr9	7			7	View
1016295	chr9	1			1	View
1402976	chr9	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GLIS3 expression and immune infiltrating cell level correlation result in HBV+ samples
GLIS3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).